β₂GPI in clinical sepsis. Plasma β₂GPI levels in 36 nonsepsis (○) patients and 35 sepsis patients (▵, ▴), who had sepsis because a Gram-negative pathogen was measured. A significant difference in β₂GPI levels could be observed between nonsepsis and sepsis patients in the intensive care unit (*P = .003), which almost returned to baseline levels after discharge (> 7 days) for both nonsepsis and sepsis patients (P = .30). Eleven sepsis patients died (▴).