Phenotypic characterization of TIMP-1^−/− stem and progenitor cells. (A-B) Percentages and absolute numbers of BM SP^KLS HSCs from WT and TIMP-1^−/− mice. (C-D) Percentages and absolute numbers of BM CD150⁺48⁻KSL HSCs from WT and TIMP-1^−/− mice. (E) Absolute numbers of BM MMPs, short-term HSCs, and LT-HSCs. (F) Percentage of BM KSLs in WT and TIMP-1^−/− mice. (G) Percentage of CLPs and common myeloid (granulocyte macrophage progenitors [GMPs], CMPs, and megakaryocyte-erythroid precursors [MEPs]) progenitors in WT and TIMP-1^−/− mice. (H) Percentage of KSL cells in the spleen of WT and TIMP-1^−/− mice. Results are reported as mean ± SEM of at least triplicate experiments. *P < .05 and ***P < .001.