Similar GVHD in C3H.SW Tg−→B6 Tg− and C3H.SW Tg+→B6 Tg+ CD8 recipients. GVHD in Tg−→Tg− and Tg+→Tg+ transplantations was similar as measured by percentage weight change (A; P > .13 comparing Tg+ and Tg− CD8 recipients from day 8 onward; P < .02 comparing each CD8 group to its respective BM-alone control from day 26 onward), incidence of skin disease (B; P = .41 comparing Tg+ and Tg− CD8 recipients; P < .014 comparing each CD8 recipient to its BM-alone control), and number of skin ulcers (C; P = .91 comparing Tg+ and Tg− CD8 recipients; P < .036 comparing each CD8 recipient to its BM-alone control). (D) Pathology scores. P values are noted in the figure.