PFS and OS in patients treated with O-FC. (A) PFS in patients (N = 61) treated with O-FC. PFS was defined as the time from randomization until disease progression or death. Median follow-up time was 8 months. (B) OS in patients (N = 61) treated with O-FC. OS was defined as the time from randomization until death. Median follow-up time was 8 months.