Correlation of chromosomal aberrations with clinical parameters.P values refer to differences between the indicated distribution patterns. Shown are the distributions of chromosomal aberrations in the 3 MPN entities PV, ET, and PMF (A) and in patients positive or negative for JAK2 mutations (B). Also shown are the associations of the number of chromosomal aberrations with disease duration (C) and patient age (D); outliers are not shown. (E) Distribution of chromosomal aberrations comparing patients in the chronic phase of the disease, patients with sMF/AP, and patients who transformed to post-MPN AML.