Typical EATL type 1 histology from one of the cases in the study. (A) The cells are large with irregularly shaped or angulated nuclei and a variable amount of cytoplasm (magnification, 250×). (B) The cells in this case expressed CD30 (magnification, 250×). The mucosa adjacent to the tumor had shortened villi (C; magnification, 100×) and “top-heavy” intra-epithelial infiltration by T cells (D; CD3 staining, magnification, 100×).