Absence of proliferation and expression of costimulatory molecules by Unc13d^jinx/jinx;Myd88^poc/poc macrophages after infection. Twelve days after LCMV infection, splenocytes from mice were stained for CD11b and F4/80 expression to evaluate the percentage of activated macrophages (A) and their absolute numbers (B). Each dot represents an individual mouse. Histograms in panels C and D show the surface expression of CD86 and CD80 on CD11b⁺F4/80⁺ macrophages, respectively. The respective MFI are reported on associated graphs. jinx, Unc13d^jinx/jinx mice; jinx;Myd88^poc, Unc13d^jinx/jinx;Myd88^poc/poc mice. Representative data of 3 independent experiments are shown for panels A and B and 2 independent experiments for panels C and D; n ≥ 4 per group of infected mice. Error bars show SEM.