Increased proportion of cycling (Ki67⁺) CD4⁺ and CD4⁺CD127⁺ T cells persistsup to M12 after ART, whereas the proportion of cycling CD8⁺ and CD8⁺CD127⁺ T-cell normalizes shortly after ART initiation. The proportion of cycling CD4⁺ (A), CD8⁺ (B), CD3⁺ (C), CD4⁺CD127⁺ (D), CD8⁺CD127⁺ (E), CD3⁺CD127⁺ (F), CD4⁺CD127⁻ (G), CD8⁺CD127⁻ (H), and CD3⁺CD127⁻ (I) is shown in the group of HIV⁺ patients (n = 30) who were followed longitudinally from M0 to M24. Circles (black) represent median values, and bars indicate interquartile range (IQR). Gray dashed lines indicate HC median values. P values (gray) at the top of the graphs represent unpaired comparison between HC and HIV⁺ at each time point, and P values (black) above the IQR bars indicate paired comparison of HIV⁺ patients at each time point during the therapy to the pretherapy level (M0). Significant P values < .01 are reported, *P = .01 > .001, **P = .001 ≥ .0001, and ***P < .0001.