Maps of unique HLA-associated adaptations in HIV-1 Gag, Pol, and Nef. Maps of unique HLA-associated adaptations (q-value ≤ 0.2) in HIV-1 Gag, Pol, and Nef, grouped for HLA-A alleles (A), -B alleles (B), and -C alleles (C). The nonadapted (susceptible/revertant) amino acids are displayed above the line in blue text and adapted amino acid are below the line in red text. Locations of published CD8 T-cell epitopes are shown as boxed labels at association sites.