Figure 1
![Figure 1. Reduced survival rate and hypersensitivity to lymphoma development in Nrf3-deficient mice treated with B[a]P compared with wild-type mice. (A-B) Kaplan-Meier survival curves are shown for wild-type mice (n = 34) (A) and Nrf3-deficient mice (n = 35) (B) treated or not with B[a]P. Control mice (○, ▵) and B[a]P-treated mice (●, ▴) are shown. (C) Kaplan-Meier survival curves (lymphoma-free) are shown for wild-type mice (n = 15) and Nrf3-deficient mice (n = 17) treated with B[a]P. *P < .05. **P < .01.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/117/6/10.1182_blood-2010-02-271460/4/zh89991066250001.jpeg?Expires=1735829417&Signature=K79z2fwsZjLLG83KX5O59knQO6jYdNtJNQuG~7dSrUysZ2BUjQSVmAujjZsUUi53v6LU-Dbm9UARIhY8Y89WRDCBKW1gX19jwJSKEtxyVZIBMjUuJSJc~DVl0RLDYC7lC8Tft~eMACUPiMNf8yO78j2NY82yI2NbfLb9~Gg2fwNjNXe7vz2wSjA8KwzH1AtRCCshIMsrM3B~9u-Zfs-h9d1ubCnyBDtr4vvmpk6t3l8hDidDD~uHgcdCoZ5Jf4IGVfMiVV8Xb-9kNYwp0Ks~gB6jIDovJv1pmAcOaHWwPTbNUN9vfAQwAL1dSYkmC~zyH5fBTJoYOxEWyAv6eoWqmw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Reduced survival rate and hypersensitivity to lymphoma development in Nrf3-deficient mice treated with B[a]P compared with wild-type mice. (A-B) Kaplan-Meier survival curves are shown for wild-type mice (n = 34) (A) and Nrf3-deficient mice (n = 35) (B) treated or not with B[a]P. Control mice (○, ▵) and B[a]P-treated mice (●, ▴) are shown. (C) Kaplan-Meier survival curves (lymphoma-free) are shown for wild-type mice (n = 15) and Nrf3-deficient mice (n = 17) treated with B[a]P. *P < .05. **P < .01.
