Figure 5
SET antagonism inhibits NHL cell growth in vivo. (A) Tumor volumes of Ramos cell tumor xenografts in SCID mice after in vivo treatment with 5 mg/kg COG449 (□) or lactated Ringer solution control (■) by subcutaneous injection. The injections were initiated on day 11, once tumors reached palpable sizes of 50-100 mm3. (B) Final tumor mass for treated and untreated Ramos tumors harvested on day 19 after implantation. ***P < .001 by t test. (C) Representative mice and their tumors.
