Figure 1
![Figure 1. Protocol schema. OS, included regimen of oral (PO) methotrexate (MTX), mercaptopurine, vincristine, and dexamethasone (during the interim maintenance [IM] phases) and single delayed intensification; OD, included regimen of PO MTX, mercaptopurine, vincristine, and dexamethasone (during the IM phases) and double delayed intensification; IS, included regimen of IV MTX and vincristine (during the IM phases) and single delayed intensification; ID, included regimen of IV MTX and vincristine (during the IM phases) and double delayed intensification. *t(4;11)(q21;q23)(q34;q11), t(9;22), balanced t(1;19)(q23;p13), and hypodiploidy with < 45 chromosomes.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/118/2/10.1182_blood-2010-12-322909/4/zh89991173790001.jpeg?Expires=1735530120&Signature=DAABQUDTPGdRA8ogyEItFugzOZGnY2TbhUjaJUH2WLrjfT~DEdZt0LYgYzTZa5s3dbSuqTq8J9i9I-5R1L6rP5moHdAMTuHi5cUyhH1eVdMfccX74CutZY9~fqGulYCuQYG2Rp~36F4qJwPEC9u3XiEtBa~nued-5P1BgkQ0RcY5taa3pOgOgnSFVmxXcfn1ynuacMCfLgaS4QuWGg8euIMflBxVYFBAe045TvHTdQLf0yTivD0UA7Q-QHd330ficltjDQdF4XIPd0vnvdWblmg~NvKDGOQGN8IpnPJ~ONB9Thoan4zBv9vpe45HvJUCzapG7vI1zZL57pG6swDevw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Protocol schema. OS, included regimen of oral (PO) methotrexate (MTX), mercaptopurine, vincristine, and dexamethasone (during the interim maintenance [IM] phases) and single delayed intensification; OD, included regimen of PO MTX, mercaptopurine, vincristine, and dexamethasone (during the IM phases) and double delayed intensification; IS, included regimen of IV MTX and vincristine (during the IM phases) and single delayed intensification; ID, included regimen of IV MTX and vincristine (during the IM phases) and double delayed intensification. *t(4;11)(q21;q23)(q34;q11), t(9;22), balanced t(1;19)(q23;p13), and hypodiploidy with < 45 chromosomes.
