Platelet trends in ITP cases. Platelet counts for the 7 patients with ITP in CAMMS223 are shown in red in panels 1 through 7, respectively. For alemtuzumab-treated patients (panels 1-6), vertical lines represent alemtuzumab dosing. Green arrowheads represent onset of ITP. ITP treatments and the timing of their administration are shown for each patient in the area above the platelet counts. Results of serum antiplatelet Ab and platelet-bound Ab testing are noted at the bottom of each panel. Plt indicates platelet; and IVIG, intravenous IgG.