The genetic distribution of various histone modifications. (A) Coverage of genetic compartments bound by various histone marks and RNA Pol II in enriched CFU-Es and late erythroblasts. Compartments are defined as: TSS (−100 bp from the TSS), proximal promoter (from −100 bp to −1 kb from the TSS), distal promoter (from −1 kb up to −10 kb from the TSS), gene body (all coding regions, including introns and exons), or intergenic (past the coding region, > −10 kb from the TSS, or not defined by one of the other categories). (B) Heat maps showing colocalization frequencies of regions in enriched CFU-Es and late erythroblasts bound by one of the various histone marks or RNA Pol II. Colors in the heat map reflect the colocalization frequency of each pair of regulators are delineated in the legend below the heat maps; red represents which regions have the most overlap; and green, exclusion of the regions.