IDO production by mature differentiated DCs from nonallergic subjects and effect of IL-10 neutralization on _GM/CCL18DC priming effect. (A) IDO production in supernatants from mature differentiated DCs. (B) Effect of IL-10 neutralization during DC differentiation on IDO production by DCs compared with isotype-treated DCs. (C) Effect of IL-10 neutralization during _GM/CCL18DC differentiation on the cytokine production by DC/T-cell cocultures compared with isotype-treated DCs. Data are mean IU/mL for IDO and pg/mL for cytokines ± SEM of n = 6 experiments for panel A, n = 3 to 6 experiments for panel B, and n = 2 experiments for panel C. *P < .05. **P < .01.