Absolute numbers of B cells per B-cell subset of 37 CVID patients and 86 healthy, age-matched controls. Patients and controls are divided into 3 age groups: 5-10 years (n = 30; A), 10-16 years (n = 28; B), and > 16 years (n = 28; C). The 3 age groups contained 6, 6, and 25 CVID patients, respectively. Boxes depict median values and 25th and 75th percentiles; whiskers, extended by interrupted lines, depict 5th and 95th percentiles for healthy, age-matched controls in the 3 age groups.