CD4⁺ naive T cells in 5 different B-cell patterns compared with controls. Absolute counts (in cells per microliter) of CD3⁺CD4⁺CD27⁺RA⁺RO⁻ naive T cells in patients with 5 different B-cell patterns compared with controls. The 5 B-cell patterns are: (1) low transitional and memory B cells; (2) low naive mature, marginal zone–like, and memory B cells; (3) low marginal zone–like and memory B cells; (4) low memory B cells; and (5) healthy marginal zone–like and memory B cells. Individual data points are displayed and bars indicate medians. Groups are compared with controls using the Mann-Whitney test. Significant values compared with healthy controls are indicated. ***P < .0005; **P < .005; *P < .05.