Effect of KLF10^−/−PACs on blood flow recovery in WT mice. (A-D) WT mice underwent femoral artery ligation to induce hindlimb ischemia. WT or KLF10^−/− CMP-, GMP-, MEP-, or HSC-derived PACs were intramuscularly injected immediately after femoral artery ligation (n = 5 per group). Mean blood flow recovery (ischemic leg/nonischemic leg) was measured by tissue Doppler imaging. *P < .05 versus WT PACs.