CAL-101 alters chemokine and cytokine secretion of CLL cells in coculture with NLCs. The bar diagrams represent the mean CLL cell supernatant concentrations for various chemokines and cytokines from CLL cells culture alone or cocultured with NLCs. Displayed are the means (± SEM) from 7 different patient samples, assessed after 24 hours. The secretion of some chemokines was significantly inhibited by CAL-101, with P < .05, as indicated by the asterisks describing the comparison of results from each culture containing CAL-101 to the results from the relevant control culture.