Induction of Rps19 deficiency leads to severe peripheral blood phenotype that progresses over time. (A) Erythrocyte number, mean corpuscular volume (MCV), neutrophil number, lymphocyte number, and platelet number (n = 12-19 per genotype at week 2; n = 6-16 per genotype at week 7). (B) Erythrocyte number after 15 days of doxycycline administration in lethally irradiated wild-type recipient mice that were transplanted with whole bone marrow cells from transgenic mice. (n = 7-9 recipients per genotype). Error bars represent SD.