Schematic representation of phenotypic abnormalities in hematopoietic compartments of AUBP-deficient mice. A generalized scheme of hematopoietic cell differentiation is shown, onto which are “mapped” the various compartments that are reported to be affected in AUF1, HUR, HUR-CD19cre, HUR-CD2cre, ZFP36, ZFP36L2, and ZFP36L1+L2-CD2cre knockout mice. Blue represents hematopoietic cell types with diminished cell numbers; and red, elevated cell numbers. HSC indicates hematopoietic stem cells; MPP, multipotent progenitor cells; CLP, common lymphoid progenitor; CMP, common myeloid progenitor; DN, double-negative (CD4⁻/CD8⁻) thymocytes; DP, double-positive (CD4⁺/CD8⁺) thymocytes; SP, single-positive (CD4⁺, CD8⁺) thymocytes; Im. B, immature B cells; FL B, follicular B cells; MZ B, marginal zone B cells; PB T, peripheral blood T cells; PB B, peripheral blood B cells; GMP, granulocyte-macrophage progenitor; CFU-G, colony factor unit granulocytes; CFU-M, colony-forming unit macrophage; MEP, megakaryocyte erythroid progenitor; CFU-Meg, colony-forming unit megakaryocytes; CFU-Eo, colony-forming unit eosinophil; CFU-Ba, colony-forming unit basophil; and BFU-E, burst-forming unit-erythroid.