Transient MCA occlusion model using the 3-VO technique. (A) Representative images of coronal sections of Pros1^+/+, Pros1^+/E, Pros1^E/E, and Pros1^+/− mouse brains. (B) Infarct volumes. No significant differences (P > .05) were observed among the groups. Symbols represent data from a single mouse. Bars represent the mean values of groups.