Pie charts representing the distribution of Ab levels. White pie, Ab− (< 6.25 AU/mL); grey pie, Ab+ (6.25-20 AU/mL); dark grey pie, Ab++ (20-200 AU/mL); black pie, Ab+++ (> 200 AU/mL) in serum samples with sufficient ASE activity (> 100 U/L), borderline ASE activity (50-100 U/L), and insufficient ASE activity (< 50 U/L) after the administration of native E coli, pegylated E coli, or Erwinia ASE.