JAK2 inhibition partially impairs the phenotypic maturation of human moDCs. (A-G) Selected phenotypic markers were assessed 48 hours after maturing moDCs with a combination of inflammatory cytokines (IL-1-β, IL-6, TNF-α, and PGE2)⁹  in the presence of either DMSO control (0.01%) or the JAK2 inhibitor TG101348 (1μM). Bar graphs show the average mean fluorescent intensities (MFI) ± SD from 4 (A,C,G) and 3 (B,E-F) independent experiments. *P < .05 by paired t test.