Characteristic renal histology in TA-TMA. Electron microscopy (×8000) from the kidney biopsy of a child who developed TA-TMA after autologous HSCT. It shows irregular electron-lucent expansion of the subendothelial zone (double arrow) and diffuse podocyte foot process fusion, a sign of damage to the glomerular filtration barrier (arrowheads). Reprinted by permission from Macmillan Publishers Ltd.¹³