Expression profiles in training set for highly significant miRNAs. We analyzed microarray measurements of 688 miRNAs in the training set of 90 samples with t tests to discover differences in expression between samples of subjects with CTCL and those of BDN subjects. The 27 miRNAs that displayed highly significant (Bonferroni corrected P < .001) and strong differences (at least 50% change) are presented in the heat map. Samples are arranged in columns, miRNAs in rows, and both are hierarchically clustered using Euclidean distance with average linkage of nodes. Red-to-yellow shades indicate increased relative expression; blue shades indicate reduced expression; green indicates median expression. The top 5 most significantly induced or repressed miRNAs are shown in bold.