Classification of CTCL and BDN. (A) PCA plot of samples from subjects with CTCL (green) and those of BDN subjects (orange) in the training set based on the 5-miRNA profile identified by the nearest shrunken centroids (NSC) algorithm. Percentages indicate percentage of variance explained by that component. (B) Classification performance in the training set using the NSC algorithm. P values were calculated using Fisher exact test. (C) PCA plot of samples in the test set based on the 5-miRNA profile identified from the training set. (D) Classification performance in the test set using the trained NSC algorithm.