qRT-PCR–based classification of samples from patients with CTCL and benign skin disease. (A) A Cp based sample score (S) were calculated for each sample. Patients are ordered by increasing values of this score. The solid line shows the cutoff between patients with CTCL (green) and patients with benign skin disease (orange). The dotted lines show the cutoffs for the low confidence region. (B) Classification performance using the cutoffs defined in panel A. P values were calculated using Fisher exact test. (C) ROC curve ROC showing the sensitivity and specificity for various cutoff values on the sample score of the samples. (D) Relative expression of the 3 miRNAs used in the classification in samples from patients with CTCL and benign skin disease. Error bars indicate ± 1 SD.