Interaction of cyclic scaffolds versus OPN-grafted peptides with immobilized α₉β₁ integrin. (A) SPR sensorgrams of SFTI-1 and SFTI-OPN. (B) SPR sensorgrams of MCoTI-II and MCo-OPN. SFTI-OPN and MCo-OPN bound to the integrin, in contrast to SFTI-1 and MCoTI-II.