Enhanced proliferation of hematopoietic progenitor cells in Dmtf1^−/− mice. BM-MNCs (A) or sorted KSLs (B) from WT, Dmtf1-KO, or Het mice were cultured with cytokines in methylcellulose medium for 10 days (n = 3) *P < .01 and **P < .05. (C) Representative dot plots showing MPPs (CD34⁺135⁺KSL), ST-HSCs (CD34⁺135⁻KSL), and LT-HSCs (CD34⁻135⁻KSL) in WT and Dmtf1-KO BM. (D) Quantification of the absolute number of KSLs, MPPs, ST-HSCs, and LT-HSCs and (G) quantification of the absolute number of progenitors (c-Kit⁺ and Sca1⁺) expressed as average ± SD per femur (n = 6). *P < .03 and *P < .05. (E) Absolute numbers of slamKSL (CD48⁻CD150⁺KSL) and (F) CD34⁻ slamKSL expressed as average ± SD per femur (n = 7).