Telomere damages are not correlated with telomere shortening in CLL cells. Telomere restriction fragment analyzes were done on B lymphocytes purified from 12 healthy donors and 20 CLL patients. Box plot showing telomere size, with corresponding Wilcoxon test–calculated P values in cells bearing (TIF⁺) or not (TIF⁻) TIF among the healthy (Co, left) or the CLL panel (CLL, right).