Shelterin component mRNA level in CLL B cells in function of TIF presence. Normalized genes expression level of TERF1, TERF2, RAP1, TINF2, ACD, and POT1. mRNA were extracted from purified B cells of 20 CLL patients demonstrating (TIF⁺) or not (TIF⁻) telomeric damages. Wilcoxon test calculated P values are indicated in each corresponding box plot.