Figure 2
Figure 2. Thromboelastometry (ROTEM) parameters. The ROTEM coagulation analyzer was used to assess blood clotting. The EXTEM assay was used according to the manufacturer's instructions. Clotting was activated by the EXTEM reagent, which contains tissue factor as the starting reagent. (A) CT, representing the initiation of clot formation; this corresponds to the reaction time. (B) CFT, the time between clot initiation and attainment of an amplitude of 20 mm. (C) MCF, reflecting the strength of the resulting clot. *P < .05 vs control; †P < .05 vs PCC35; ‡P < .05 vs PCC50DIC−. ◊, not detectable.

Thromboelastometry (ROTEM) parameters. The ROTEM coagulation analyzer was used to assess blood clotting. The EXTEM assay was used according to the manufacturer's instructions. Clotting was activated by the EXTEM reagent, which contains tissue factor as the starting reagent. (A) CT, representing the initiation of clot formation; this corresponds to the reaction time. (B) CFT, the time between clot initiation and attainment of an amplitude of 20 mm. (C) MCF, reflecting the strength of the resulting clot. *P < .05 vs control; †P < .05 vs PCC35; ‡P < .05 vs PCC50DIC−. ◊, not detectable.

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