Day 9 bronchoalveolar lavage fluid fibrinolytic activity. PAI-1^−/− and WT mice were treated with intratracheal bleomycin (1.15 μg/kg in 50 μL of sterile PBS) on day 0. On day 8, subgroups of PAI-1^−/− animals were treated with either intraperitoneal injections of PBS or 100 μg/injection every 12 hours of PAI-1(V+P+), PAI-1(V+P-) or PAI-1(V-P+). WT mice received the same dosing regimen of intraperitoneal PBS. On day 9, 1 hour after the last injection, BAL fluid was collected from each animal and the amount of fibrinolytic activity was measured using a clot lysis assay. Results are reported as a scatter plot of t_1/2, which represents the time in minutes required for 50% of the clot to be degraded (as assessed by absorbance at 405nm). N = 17-22 mice. Groups are statistically compared with a Kruskal-Wallis test with post hoc group comparison using the Dunn Multiple Comparison Test.