Effect of neutralizing murine IL-7 on CD127 and surface IgM expression on sorted CD98^hi (CD127⁺) cells. (A) CD19⁺ cells from MS-5 xenogeneic cultures were stained for expression of CD98 and CD127; the expression of CD127 is correlated with high CD98 expression. (B) Pre-sort sIgM and CD98 phenotype (left), post-sort analysis of sorted sIgM-CD98^hi cells (middle), and CD127 expression on sorted sIgM-CD98^hi (right). (C-D) Surface IgM (C) and CD127 (D) expression on CD19⁺CD98^hisIgM⁻ cells after 6 days of culture on MS-5 in the absence or presence of neutralizing anti–mIL-7. Filled histograms indicate unstained control cells (B-D).