NFS used to evaluate gross clinical neurologic status for the cohort at pre-HCT and post-HCT time points. Note that a score of “0” denotes absence of clinical signs of cerebral disease. Maximal signs within a domain score the total of all grades within that domain. For example, 3 indicates a patient with total urinary or fecal incontinency; 1, the sum of episodes of incontinency; and 2, total incontinency.