ADAMTS13 deficiency accelerates atherosclerotic lesion formation in the aorta. (A) Representative Oil red O-stained aortae from male mice on a high-fat Western diet beginning at 6 weeks until they were killed at 4 months of age (ie, 10 weeks on high-fat Western diet). (B) Quantification of en face lesion area from male mice (N = 10-12/group). (C) Quantification of en face lesion area from female mice (N = 10-15/group). Each dot represents a single mouse. Horizontal bars represent mean values.