ADAMTS13 deficiency exacerbates atherosclerosis in ApoE^−/− mice fed a normal chow diet. (A) Representative Oil red O-stained aortae from ApoE^−/− and Adamts13^−/−/ApoE^−/− male mice fed a normal chow diet until 4 months of age. (B) Quantification of en face lesion area in the aorta (N = 10/group). (C) Representative photomicrographs of VerHoeffs/Van Geison-stained aortic sinuses from ApoE^−/− and Adamts13^−/−/ApoE^−/− male mice fed a normal chow diet until 4 months of age. Bar represents 200 μm. (D) Quantification of lesion area in the cross sections of aortic sinus (N = 9 or 10/group). Each dot represents a single mouse. Horizontal bars represent mean values.