CFS tumor suppressor genes FHIT, WWOX, and GRID dot plot in PEL. Dot plot representation of markers distributed along the chromosome. (A,C) The loss of FHIT, WWOX, and GRID2 from chromosomes 3, 16, and 4, both in the 6.0 and 500K SNP array are shown. The markers (from each of the 13 PELs) are represented by black dots on a log₂ scale (amplification denoted by dots above and deletion by dots below the normal 0 line) with the cytoband at the base of plot. The dots identified by ∧ represent alterations that only occurred in 1 of 13 PELs and were thus considered exceptions. (B,D) Data represent 6 nonlymphoma tumor samples and 5 non-PEL lymphoma controls, respectively.