Quantification of CNV in PEL, separated by EBV status. (A) There are significantly more amplifications in EBV-negative PELs than in EBV-positive PELs. (B) Although there is increased deletion of markers in the EBV-negative population, there difference is less conclusive. (C) PCA shows that PEL cells in culture form 2 distinct groups correlative with their EBV infection status: blue indicates EBV(−) and brown EBV(+) samples. The x-, y-, and z-axes represent PC1, PC2, and PC3, respectively, accounting for 18.9%, 18.1%, and 11.3% of variability in the data.