OS in patients with both-risk, standard-risk, or high-risk diseases according to the locus of HLA mismatch in the GVH direction and the number of mismatches in the HVG direction. Survival rates in patients with HLA-A, HLA-B, and HLA-DR Ag mismatches in the GVH direction were compared with the log-rank test (A,C,E). Survival rates in patients with 0-1 and 2-3 mismatches in the HVG direction were compared with the log-rank test (B,D,F). Survival rates of the 8/8-MUD group are shown for visual comparison.