Platelet counts and clearance. (A) Peripheral platelet counts in control and FlnA^loxP PF4-Cre mice. Results represent mean ± SD (n = 9). #P < .05. (B) Average survival of transfused platelets in mice. CMFDA-labeled control and FlnA-null platelets were injected into control mice. Results are the percentage of labeled platelets in the circulation relative to time 1 minute, represent the mean ± SD of 3 mice, and are representative of 3 independent experiments.