Comparison of N9-GP and rFIX in human hemophilia B whole blood. TEG traces of whole blood from a severe (A) and a moderate (B) HB patient before (stippled line) and after spiking with 28nM N9-GP (black line) or rFIX (gray line). Clot formation was induced by addition of kaolin. R-time and MTG values are shown as a function of added N9-GP or rFIX in blood from the same (C) severe or (D) moderate patient. The normal range ± 2 SD are indicated by horizontal lines.