ddx18^{hi1727/hi1727} myeloid and developmental defects can be rescued with human DDX18. (A-D) Lateral view, head to the left embryos at 27 hpf. WISH for mpx in ddx18^hi1727 siblings (A,C) and mutants (B,D), after injection of control (mCherry encoding; A-B) or human DDX18-encoding (C-D) RNA. Expression of the human DDX18 results in rescue of the ddx18^{hi1727/hi1727} mutant phenotype from both developmental and myeloid defects. (E) Scatter plot showing number of mpx-expressing cells per embryo. Line denotes the mean value. Statistical analysis performed using the Student t test with Welch correction. ns indicates not significant.