Erythroid phenotypes of V205GR neonates. (A) Erythroid parameters of V205GR neonates. Eight WT, 5 V205GR-A, and 3 V205GR-B neonates aged 0 to 3 days old were used. (*P < .05, **P < .01). (B-C) Histologic examination of 2-day-old neonatal spleens of V205GR-A (bottom panels) and WT littermate (top panels). Scale bars correspond to 0.5 mm in panel B and 100 μm in panel C, respectively. (D) The expression profile of CD71 and TER119 in the c-Kit⁻ erythroid population. Mononuclear cells derived from 1-day-old neonatal spleens of V205GR-A (bottom panel) and WT littermates (top panel) were used. The frequencies and mean intensity values of TER119⁺ cells were shown in the panels.