Mice with FLT3/ITD-NHD13 mutations develop AML. Comparison of cell surface staining of FLT3/ITD-NHD13 mice to WT, NHD13, and FLT3/ITD littermates at a 3-month time point. Bone marrow and spleen were evaluated for the expression of (A) mature myeloid markers, (B) coexpression of Mac-1/Gr-1 and B220, (C) B-cell markers, and (D) T-cell markers.