The survival tree model (OS). The tree shows the partitioning of the 318 intermediate-risk AML into 4 groups with more similar survival characteristics. Kaplan-Meier estimates of the survival curves for each of the groups attached at the bottom of the tree. Group I (n = 132) consists of patients with CD34 expression ≤ 0.398. Group II (n = 143) are patients with CD34 expression > 0.398, IDH2 wild type CEBPADM absent. Group III is characterized by CD34 expression > 0.398, IDH2 mutation present, and no CEBPADM. Group IV includes patients with CD34 expression > 0.398 and CEBPADM.