Proportion of B-lineage cell types in the BM and spleen. (A) Different B-cell subsets in the BM of WT, B/WcKO, and WKO mice were analyzed by flow cytometry with the indicated cell surface markers. Results from individual mice are shown. Statistical significance was assessed with 1-way ANOVA and Bonferroni posttest analysis. **P < .01 and ***P < .001. (B) Different B-cell subsets in the spleen of WT, B/WcKO, and WKO mice were analyzed by flow cytometry with the indicated cell surface markers. Data from individual mice are shown. Statistical significance was assessed with 1-way ANOVA and Bonferroni posttest analysis. *P < .05, **P < .01, and ****P < .0001.