NHERF-2 is a molecular switch that controls endothelial and tumor migration. In the presence of NHERF-2, rho A activation predominates, while in the absence of NHERF-2, a WT-1/podocalyxin/rac/reactive oxygen signaling pathway is activated.
NHERF-2 is a molecular switch that controls endothelial and tumor migration. In the presence of NHERF-2, rho A activation predominates, while in the absence of NHERF-2, a WT-1/podocalyxin/rac/reactive oxygen signaling pathway is activated.
