Absence of Jam-A accelarate pulmonary thromboembolism. (A) Survival curve of Jam-Awt/wt and Jam-Agt/gt mice after induction of pulmonary thromboembolism (n = 18). (B) Representative images of lung isolated from Jam-Awt/wt and Jam-Agt/gt injected with PBS or PBS and Evans blue or a mixture of collagen and epinephrine solution. (C) H&E-stained sections of lungs.